Kristoffer Famm and colleagues unveil a multidisciplinary initiative to develop medicines that use electrical impulses to modulate the body’s neural circuits... At the Massachusetts Institute of Technology, researchers (including E.S.B.) are collaborating to map and modulate neural circuits using technologies that range from optogenetics to scalable, automated electrophysiology — and they are distributing the genetic codes, hardware and software necessary to put these inventions into practice... the company will launch a US$1-million prize for innovation...